Mechanobiology

Mechanobiology

Labs studyingÌýMechanobiology

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Calve Lab

The Calve Musculoskeletal ExtracellularÌý MatrixÌý Lab characterizes the material properties of assembling tissues to establish design parameters for regenerative therapies. They are particularly interested in the composition and spatial organization of the extracellular matrix, its influence on muscle mechanical properties, and the application of hyaluronic acid to muscle repair and regeneration.

Ding Lab

The Ding Biomedical Microfluidics Lab are innovators in engineering cell functions for cell-based immunotherapy with a goal of reducing costs of disease diagnostics and therapeutics. They work at the frontiers of micro/nano engineering, biomedical engineering, acoustics, electronics, and other applied physics.Ìý

Ferguson Lab

The Ferguson Biomechanics and Biomimetic Lab studies how the microstructure, composition, and material properties of tissues influence mechanical behavior. Further, they examine how these properties change with disrupted mechanical loading, aging, or disease.

Jayaram Lab

The Jayaram Animal Inspired Movement and Robotics Laboratory (AIM-RL) combines biology and robotics to uncover the principles of robustness underlying successful animal locomotion in natural environments and to inspire the design of next generation novel robots for real-world operation.Ìý

Lynch Lab

The Lynch Lab studies the skeletal mechanical environment and its regulation of cancer using mechanical loading model systems to correlate cellular function with cancer pathogenesis, tissue-level changes in tumor burden, and skeletal tissue strength. They aim to identify targets for treating and preventing bone metastases as well as cancer-associated reductions in bone strength.

Mukherjee Lab

The Mukherjee Lab investigates the flow, transport, and mechanical underpinnings of physiological processes and develops tools for disease biomechanics, medical device design, treatment planning, and drug delivery. A primary application area is in cardiovascular and cerebrovascular processes in healthy and diseased states, like stroke, thrombosis, and embolisms.Ìý

Neu Lab

The Neu Soft Tissue Bioengineering Lab develops technology for fundamental study and engineering of connective and cardiac tissues to inform new therapies for disorders of the connective and cardiac tissues, including arthritis and fibrosis. Biomechanics is a central lab theme, and they span multiple engineering and biology disciplines, including mechanical, electrical, micro/nanotechological, biochemical, and physiological subspecialties.Ìý

Perkins Lab

The Perkins Lab develops and applies high-precision single-molecule techniques—atomic force microscopy (AFM) and optical traps—to address outstanding questions in a wide range of biological systems, from DNA-protein interactions to protein folding mechanobiology.Ìý

Welker Lab

The Welker Lab works on movement assistive devices at the intersection of biomechanics, haptics, and robotics. Their work on the human-device as a system aims to improve movement for individuals with impairments or injuries and to reduce injury or prevent fatigue in the healthy population.